The GDC provides user-friendly and interactive Data Analysis, Visualization, and Exploration (DAVE) Tools supporting gene and variant level analysis. T4a: The tumor has spread into nearby structures, such as the thyroid gland, the arteries that carry blood to the brain, or the esophagus. There is no spread to other parts of the body (T4, any N, M0). If the cancerous tissue looks very different from healthy tissue, it is called "poorly differentiated" or a "high-grade tumor." There is no ENE. Stage I: The tumor is 2 cm or less in size, but cancer has not spread to lymph nodes or other parts of the body (T1, N0, M0). When cancer has spread through a lymph node and into the tissues directly surrounding it, it is called extranodal extension (ENE). Stage II: This stage describes a tumor that has spread to some nearby areas but has not spread to lymph nodes or to distant parts of the body (T2, N0, M0). Cancer may have spread to 1 lymph node, but it has not spread to other parts of the body (T4a, N0 or N1, M0). Lymph nodes in other parts of the body are called distant lymph nodes. The tumor is larger than 4 cm or has spread to the epiglottis, but the cancer has not spread to lymph nodes or other parts of the body (T3, N0, M0). N3a: The cancer is found in a lymph node and is larger than 6 cm. There is no ENE. If it has spread to the lymph nodes, it is only to a single lymph node on the same side of the primary tumor. Here are more details on each part of the TNM system for oral and oropharyngeal cancer. Where is it located? The grade describes how much cancer cells look like healthy cells when viewed under a microscope. If cancer has spread to lymph nodes, none of the cancer is larger than 6 cm and it only affects lymph nodes on the same side of the body as the primary tumor. One tool that doctors use to describe the stage is the TNM system. Tumor size is measured in millimeters (mm) and centimeters (cm). The “N” in the TNM staging system stands for lymph nodes. Where is it located? The tumor is any size. N2b: Cancer has spread to more than 1 lymph node on the same side as the primary tumor, and none measures larger than 6 cm. T3: The tumor is larger than 4 cm, or it is any tumor with a depth of invasion greater than 10 mm. N3: The cancer is found in a lymph node and is larger than 6 cm. HER2 is a transmembrane tyrosine kinase receptor and is expressed by, and involved in the growth of, some cancer cells. The "M" in the TNM system describes whether the cancer has spread to other parts of the body, called distant metastasis. There is no ENE. Doctors use the results from diagnostic tests and scans to answer these questions: 1. Cancer has spread to more than 4 lymph nodes. Metastasis (M): Has the cancer spread to other parts of the body? All rights reserved worldwide, ‹ Oral and Oropharyngeal Cancer - Diagnosis, Oral and Oropharyngeal Cancer - Types of Treatment ›, Oral and Oropharyngeal Cancer: Stages and Grades. There are 5 stages: stage 0 (zero) and stages I through IV (1 through 4). There are different stage descriptions for different types of cancer. T4: The tumor has invaded the larynx, muscle of the tongue, muscles in the jaw, roof of the mouth, or jawbone. The cancer has not spread to lymph nodes or other parts of the body (T2, N0, M0). These tiny, bean-shaped organs help fight infection. G3: The cells don’t resemble healthy tissue (poorly differentiated). The next section in this guide is Types of Treatment. We know 65 definitions for ENE abbreviation or acronym in 8 categories. Cancer has spread to 1 or more lymph nodes on either side of the body, and none is larger than 6 cm. Specific tumor stage information is listed below and has been divided into an outline of tumors of the larynx and tumors of the hypopharynx. The cancer may involve the lymph nodes, but it has not spread to other parts of the body (T4b, any N, M0). G4 (hypopharynx only): The cells don’t look like healthy tissue at all (undifferentiated). Cancer has spread to 1 or more lymph nodes, but none is larger than 6 cm. The cancer is found in a lymph node and is larger than 6 cm, but there is no ENE, or there is ENE in any lymph node. 2. Font size: 5-FU: 5-FluoroUracil (anti-cancer drug) Rate it: 6-MP: 6-MercaptoPurine (anticancer drug) Rate it: ... Get instant explanation for any acronym or abbreviation that hits you anywhere on the web! Metastasis (M): Has the cancer spread to other parts of the body? Use the menu to choose a different section to read in this guide. T3: The tumor is larger than 4 cm or has spread to the epiglottis, which is the flap of cartilage that diverts food into the esophagus. There is no ENE. T1: The tumor is limited to the vocal cords, but it does not affect the movement of the cords. ON THIS PAGE: You will learn about how doctors describe a cancer’s growth or spread, as well as what the cancer cells look like under a microscope. Need to know how Cancer is abbreviated in Medical? Cancer may have spread to 1 lymph node, but it has not spread to other parts of the body (T4a, N0 or N1, M0). Cancer is in 1 lymph node on the same side as the primary tumor, and it is 3 cm or smaller, with no ENE. Acronym / Abbreviations Categories: Astronomy Acronyms (825): Atmospheric Research Center Acronyms (4622): Business And Finance (171): Chatting Acronyms (115): Chemistry Acronyms (14383): Computer Acronyms (Common) (249) Computer And Internet Acronyms (836): Human Genome Acronyms (308): Medical Acronyms (501): Medical Acronyms (Slang) (421) NASA Acronyms (8940): … If so, where and how many? Cancer has not spread to other parts of the body (T4b, any N, M0). Stage 0 (zero) is only used for non-HPV-related oropharyngeal cancer. Clinical N is used for patients who have not received a neck dissection (see “Surgery” in Types of Treatment). The tumor may be small or it may have invaded nearby structures, like the larynx, muscles of the tongue or jaw, roof of the mouth, or jawbone. There is significant spread to the lymph nodes but no distant metastasis (T1–T4a, N2, M0). This is a very early cancer where cancer cells are found only in 1 layer of tissue. Information about the cancer’s stage and grade will help the doctor recommend a specific treatment plan. The stage provides a common way of describing the cancer, so doctors can work together to plan the best treatments. Doctors combine the T, N, and M information to say what stage the cancer is. E. ECF Esophageal Cancer, Gastric Cancer ECX Esophageal Cancer, Gastric Cancer EOF Esophageal Cancer, Gastric Cancer EOX Esophageal Cancer, Gastric Cancer EP Testicular Cancer, Thymoma EPOCH Non-Hodgkin's Lymphoma EPOCH+R Non-Hodgkin's Lymphoma ESHAP Non-Hodgkin's Lymphoma. T4a: The tumor has spread to the cricoids, the ring-shaped cartilage near the bottom of the larynx, or thyroid cartilage and/or the tissue beyond the larynx. The TNM system is the most widely used cancer staging system. Stages may also be divided into smaller groups that help describe the tumor in even more detail. Stage III: Either of the following applies: The tumor is larger than 4 cm, or it is any tumor with a depth of invasion greater than 10 mm. Or, cancer has spread to many lymph nodes, and at least 1 has ENE. N0 (N plus zero): There is no evidence of cancer in the regional lymph nodes. There is no spread to other parts of the body (any T, N3, M0). As the flagship journal of the American Cancer Society, CA: A Cancer Journal for Clinicians reaches a diverse group of oncology specialists, primary care clinicians, and other professionals who interact with cancer patients. pN0 (N plus zero): There is no evidence of cancer in the regional lymph nodes. Cancer has not spread to other parts of the body (any T, N3, M0). If so, where and how much? Stage I: The tumor is 4 cm or smaller. T3: The tumor is limited to the larynx and affects the vocal folds. Or, there is ENE in a single lymph node on the opposite side of the primary tumor that is 3 cm or smaller. Stage III: The tumor is larger than 4 cm or it invades nearby structures. There are 4 or 5 stages, depending on the diagnosis. Stage I: The tumor is 4 cm or smaller. Healthy tissue usually contains many different types of cells grouped together. HPV-related oropharyngeal cancer does not have a separate grading system. This is a short list of common abbreviations you may have seen on a doctor's notepad; a prescription drug package or bottle; … T4: This is moderately advanced or very advanced local disease. When cancer has spread through a lymph node and into the tissues directly surrounding it, this is called extranodal extension (ENE). Cancer has not spread to other parts of the body (T3, N0 to N2, M0). There is no spread to other parts of the body (T3 or T4, pN2, M0). There is no ENE. Node (N): Has the tumor spread to the lymph nodes? If cancer has spread to a lymph node, it is to only 1 node on the same side as the primary tumor, and the cancer is 3 cm or smaller, with no ENE. The Free Dictionary Doctors use the results from diagnostic tests and scans to answer these questions: Tumor (T): How large is the primary tumor? Cancer has not spread to other parts of the body (T1 to T4a, N2, M0). Cancer has not spread to other parts of the body (T1 to T4a, N2, M0). If the cancerous tissue looks very different from healthy tissue, it is called "poorly differentiated" or a "high-grade tumor." T2: The tumor has spread to the supraglottis and/or the subglottis. The cancer involves 4 or fewer lymph nodes. Doctors use diagnostic tests to find out the cancer’s stage, so staging may not be complete until all the tests are finished. Used with permission of the American College of Surgeons, Chicago, Illinois. In general, the lower the tumor’s grade, the better the prognosis. The tumor is larger than 4 cm or has spread to the epiglottis. T4a: The tumor has spread through the thyroid cartilage and/or the tissue beyond the larynx. A centimeter is roughly equal to the width of a standard pen or pencil. Since there are many lymph nodes in the head and neck area, the doctor’s careful assessment of lymph nodes is an important part of staging. For example, HER2 is overexpressed in 18% to 20% of invasive breast cancers and affects treatment as well as prognosis of breast cancers.. Also called c-erbB-2 or neu; also written HER-2. Cancer has not spread to other parts of the body (T1–T4a, N2, M0). What does ENE Stand For in Medical & Science ?. Knowing whether ENE is present plays an important role in the evaluation of lymph nodes in oral and oropharyngeal cancers that are not related to HPV. Tumor size is measured in centimeters (cm). If the cancer does return, there will be another round of tests to learn about the extent of the recurrence. Stage IVA: Either of the following applies: There is an invasive tumor. This laboratory technique allows clinicians to count blood cells in a sample. For ENE we have found 65 definitions. TX: The primary tumor cannot be evaluated. Stage II: The tumor is between 2 cm and 4 cm, but cancer has not spread to lymph nodes or other parts of the body (T2, N0, M0). M1: Cancer has spread to other parts of the body. Or, cancer has spread to many lymph nodes, and at least 1 has ENE. Their settings may range from a summer camp for Boy Scouts in the forest, to a group of terminally ill cancer patients during a weekend retreat at a hotel. 2. 3. showing only Science & Medicine definitions . It may also invade the space inside the larynx and/or the cartilage of the thyroid. Careful assessment of lymph nodes is an important part of staging. Cancer has not spread to other parts of the body (T0 to T2, N0 or N1, M0). T1a: The tumor is only in the right or left vocal cord. 3. One tool that doctors use to describe the stage is the TNM system. Komrokji RS, Padron E, List AF. Doctors assign the stage of the laryngeal or hypopharyngeal cancer by combining the T, N, and M classifications. There are 2 methods of categorizing N in the TNM system: clinical and pathological. Using the TNM system, the "T" plus a letter or number (0 to 4) is used to describe the size and location of the tumor. Cancer has not spread to other parts of the body (T0 to T2, N2, M0). The TNM system differs depending whether the diagnosis is oral cancer, oropharyngeal cancer, or HPV-related oropharyngeal cancer. The cancer has not spread to lymph nodes or other parts of the body (T3, N0, M0). N2a: Cancer has spread to 1 lymph node and is 3 cm or smaller, but there is ENE. The next section in this guide is Types of Treatment. Doctors use diagnostic tests to find out the cancer’s stage, so staging may not be complete until all of the tests are finished. Node (N): Has the tumor spread to the lymph nodes? Enloe meets your urgent medical care needs with two Prompt Care Clinics in Chico, Calif. Link/Page Citation Category Filters; All definitions (16) Information Technology (3) Military & Government (3) Science & Medicine (2) Organizations, Schools, etc. Stage IVC: Cancer has spread to other parts of the body (any T, any N, M1). Specific tumor stage information is listed below. Lymph nodes may or may not be involved. Knowing whether ENE is present plays an important role in the evaluation of lymph nodes in hypopharyngeal cancer. The tumor has invaded the larynx, muscle of the tongue, muscles in the jaw, roof of the mouth, or jawbone. Abbreviations, acronyms, and medical terminology are used for many conditions, and for instructions on medication prescribed by your doctor. Staging is a way of describing where a cancer is located, if or where it has spread, and whether it is affecting other parts of the body. It is a very early cancer where cancer cells are found in only 1 layer of tissue. N2c: Cancer has spread to more than 1 lymph node on either side of the body, and none measures larger than 6 cm. The tumor has invaded the muscles and bones that form the mouth or the base of the skull, and/or it encases the internal arteries. The tumor has invaded the larynx, muscle of the tongue, muscles in the jaw, roof of the mouth, or jawbone. Use the menu to see other pages. CANS T3: The tumor is larger than 4 cm or has spread to the epiglottis, which is the flap of cartilage that keeps food from entering the airway during swallowing. All rights reserved worldwide, ‹ Laryngeal and Hypopharyngeal Cancer - Diagnosis, Laryngeal and Hypopharyngeal Cancer - Types of Treatment ›, Laryngeal and Hypopharyngeal Cancer: Stages and Grades. Stage IV: Cancer has spread to other parts of the body (any T, any N, M1). Here are more details on each part of the TNM system for both laryngeal cancer and hypopharyngeal cancer. The cancer has not spread to lymph nodes or other parts of the body (T1, N0, M0). Cancer.Net GuideOral and Oropharyngeal Cancer. In general, pathological evaluation provides the most information to determine a patient's prognosis. © 2005-2021 American Society of Clinical Oncology (ASCO). N3b: There is ENE in a single lymph node on the same side as the primary tumor, and it is larger than 3 cm. Cancer is in 1 lymph node on the same side as the primary tumor, and it is 3 cm or smaller, with no ENE. Brain Metastatic Breast Cancer: Rate it: BMJ: British Medical Journal: Rate it: BMPM: Benign Multicystic Peritoneal Mesothelioma: ... Get instant explanation for any acronym or abbreviation that hits you anywhere on the web! Pneumonia is an infectious disease of the lungs, and is caused by various bacteria, viruses or fungal infections. The stage groups for HPV-related oropharyngeal cancer differ depending on whether the lymph nodes have been assessed clinically or pathologically. Cancer has not spread to other parts of the body (T1–T3, N1, M0). The original and primary source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017), published by Springer International Publishing. Evaluation of nodes can be clinical or pathological. There are 10 millimeters in 1 centimeter. N2c: Cancer has spread to more than 1 lymph node on either side of the body, and none measures larger than 6 cm. Medical terminology for cancer : Abbreviations and Acronyms for Oncology Medical » Oncology Abbreviations Browse 1,402 acronyms and abbreviations related to the Oncology terminology and jargon. Trusted, compassionate information for people with cancer and their families and caregivers, from the American Society of Clinical Oncology (ASCO), the voice of the world’s cancer physicians and oncology professionals. NX: The regional lymph nodes cannot be evaluated. Chapter 111: Myelodysplastic syndromes. The doctor compares the cancerous tissue with healthy tissue. The tumor is any size, but it has not invaded nearby structures of the oral cavity. Stage may also be divided into smaller groups that help describe the tumor in even more detail. Your abbreviation search returned 16 meanings. There is no ENE. T3: The tumor is limited to the larynx and paralyzes at least 1 of the vocal cords. Metastasis (M): Has the cancer spread to other parts of the body? pN2: Cancer has spread to more than 4 lymph nodes. Recurrent: Recurrent cancer is cancer that has come back after treatment. T1: The tumor is 2 cm or less at its greatest dimension. Lymph nodes may or may not be involved. There is no ENE. ENE is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms ENE - What does ENE stand for? NX: The regional lymph nodes cannot be evaluated. A centimeter is roughly equal to the width of a standard pen or pencil. Home » Cancer Registration & Surveillance Modules » Cancer & Medical Terminology » Abbreviations, Symbols, & Acronyms » Abbreviation Index Section Menu Cancer Registration & Surveillance Modules Cancer has not spread to other parts of the body (T1 to T3, N1, M0). The "M" in the TNM system describes whether the cancer has spread to other parts of the body, called distant metastasis. Staging is a way of describing where the cancer is located, if or where it has spread, and whether it is affecting other parts of the body. Movement of the vocal cords may be affected. The stage provides a common way of describing the cancer, so doctors can work together to plan the best treatments. These tests and scans are often similar to those done at the time of the original diagnosis. Stage I: The tumor is 2 cm or smaller, and the depth of invasion is 5 mm or less. T3: The tumor is larger than 4 cm or has spread to the larynx or esophagus. The tumor has not invaded nearby tissues, except the epiglottis. Cancer has spread to more than 4 lymph nodes. Pathological N is used for those who have had a lymph node dissection. Where is it located? The tumor has invaded muscles and bones in the region of the mouth; the nasopharynx, which is the air passageway at the upper part of the throat behind the nose; or the base of the skull, or the tumor encases the carotid artery. Metastasis (M): Has the cancer spread to other parts of the body? Stage II: The tumor is between 2 cm and 4 cm, but cancer has not spread to lymph nodes or other parts of the body (T2, N0, M0). G2: The cells are only moderately differentiated. Or, there is ENE in a single lymph node on the opposite side of the primary tumor that is 3 cm or smaller. G1: The cells look more like normal tissue (well differentiated). There is no spread to other parts of the body (T0 to T2, pN2, M0). medical - cancer, Internet Abbreviations and Acronyms, Web's acronyms and abbreviations resource. The name “BRCA” is an abbreviation for “BReast CAncer gene.” BRCA1 and BRCA2 are two different genes that have been found to impact a person’s chances of developing breast cancer. T4b: The tumor has invaded muscles and bones in the region of the mouth; the nasopharynx, which is the air passageway at the upper part of the throat behind the nose; or the base of the skull, or the tumor encases the carotid artery. N2a: Cancer has spread to 1 lymph node and is 3 cm or smaller, but there is ENE. Stage II: Either of the following applies: The tumor is 4 cm or smaller. Or, the tumor is larger than 2 cm but not larger than 4 cm, and the depth of invasion is 10 mm or less. HER2: Abbreviation for human epidermal growth factor receptor 2. There are different stage descriptions for different types of cancer. High levels can be a sign of cancer. pN1: The cancer has spread to 1 to 4 lymph nodes. A pathology report is a medical document that gives information about a diagnosis, such as cancer.To test for the disease, a sample of your suspicious tissue is sent to a lab. Using the TNM system, the "T" plus a letter or number (0 to 4) is used to describe the size and location of the tumor. One tool that doctors use to describe the stage is the TNM system. There is no ENE. Stage IVA: Either of the following applies: The tumor has invaded nearby structures in the mouth, such as the jaw, sinuses, or skin of the face. The cancer is found in a lymph node and is larger than 6 cm, but there is no ENE; or there is ENE in any lymph node. T4a: The tumor has spread to the thyroid cartilage and/or the tissue beyond the larynx. Stage 0: There is carcinoma in situ, with no spread to lymph nodes or other parts of the body (Tis, N0, M0). Stage III: Either of the following applies: A larger tumor with no spread to regional lymph nodes or metastasis (T3, N0, M0). Cancer has not spread to other parts of the body (T3 or T4, pN0 or pN1, M0). The cancer’s grade can help the doctor predict how quickly the cancer will spread. As well as many widely used medical abbreviations this text includes abbreviations that have meaning only within oncology, sub-specialities or even particular organisations. If the cancer does return, there will be another round of tests to learn about the extent of the recurrence. Please look for them carefully. Recurrent cancer is cancer that has come back after treatment. M1: The cancer has spread to other parts of the body. Tumor (T): How large is the primary tumor? If the cancer looks similar to healthy tissue and has different cell groupings, it is called "differentiated" or a "low-grade tumor." Enloe Medical Center provides patient centered comprehensive care including cardiac surgery, stroke, neurosurgery, orthopedics, cancer care, maternity care and bariatrics. There is no ENE. ON THIS PAGE: You will learn about how doctors describe a cancer’s growth or spread. T1: The tumor is located in a single area above the vocal cords that does not affect the movement of the vocal cords. Or, cancer has spread to a single lymph node on the same side as the primary tumor and is larger than 3 cm but not larger than 6 cm, and there is no ENE. Cancer has spread to 1 or more lymph nodes, but none is larger than 6 cm. This is called the stage. Stage IVB: Either of the following applies: There is extensive spread to the lymph nodes but no distant metastasis (any T, N3, M0). Lymph nodes near where the cancer started are called regional lymph nodes. Use the menu to choose a different section to read in this guide. If so, where and how much?The results are combined to determine the stage of cancer for each person. The most common pneumonia is caused by viruses, and the treatment is usually symptomatic (anti caugh and fever, etc. Cancer has not spread to other parts of the body (T1 to T3, N1, M0). Doctors also describe oral and oropharyngeal cancer by its grade (G). Pathological evaluation is based on what is found during surgery plus the results of physical examinations, imaging scans, and biopsies. Lymph nodes in other parts of the body are called distant lymph nodes. The tumor is larger than 4 cm or it invades nearby structures. N3b: There is ENE in a single lymph node on the same side as the primary tumor, and it is larger than 3 cm. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Answering questions about a history of prostate cancer in your family can help your doctor make an accurate diagnosis. The American Cancer Society medical and editorial content team. Get the top ENE abbreviation related to Medical. The “N” in the TNM staging system stands for lymph nodes. If lymph nodes are involved, none of the cancer is larger than 6 cm. The results are combined to determine the stage of cancer for each person. Used with permission of the American College of Surgeons, Chicago, Illinois. N1: The cancer has spread to a single lymph node on the same side as the primary tumor, and the cancer found in the node is 3 cm or smaller. Stage I: This stage describes a small tumor with no spread to lymph nodes or distant metastasis (T1, N0, M0). Cancer has not spread to other parts of the body (T0 to T2, pN0­ or pN1, M0). M0: The cancer has not spread to other parts of the body. Possible ENE meaning as an acronym, abbreviation, shorthand or slang term vary from category to category. Knowing the stage helps the doctor to decide what kind of treatment is best and can help predict a patient’s prognosis, which is the chance of recovery. These tiny, bean-shaped organs help fight infection. If your doctor suspects PNH, he or she may order a variety of blood tests to confirm the diagnosis.. Over the past several years, flow cytometry has become the gold standard for making the diagnosis.